Lassa fever practice challenges in Nigeria

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Lassa Fever, Nigeria, 2005–2008

To the Editor: Lassa fever affects ≈100,000 persons per year in West Af-rica (1). The disease is caused by Las-sa virus, an arenavirus, and is associated with bleeding and organ failure. The case-fatality rate in hospitalized patients is 10%–20%. The reservoir of the virus is multimammate mice (Mastomys natalensis). Investigations in the 1970s and 1980s pointed to the existence of 3 disease-end...

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Lassa Fever, Nigeria, 2003 and 2004

The patient was successfully extubated. He was transferred to a pneumology ward on day 9 and discharged on day 15. Antimicrobial treatment was stopped on day 10. Most nonhuman strains of V. metschnikovii are usually found in aquatic habitats (e.g., lakes and marine waters). Human clinical infections with this bacterium are rare; however, cases of epidemic diarrhea caused by V. metschnikovii hav...

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Awareness of Lassa Fever in a Rural Community in South West Nigeria

Background: Lassa fever is an acute, virulent viral haemorrhagic illness with high morbidity and mortality rates. Its awareness remain low in sub urban or rural community. This study was carried out to assess the awareness of Lassa fever of a rural community in the south western part of Nigeria. Methodology: A descriptive cross sectional study of 122 respondents prior to a sensitization semina...

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Lassa fever: the challenges of curtailing a deadly disease

Today Lassa fever is mainly a disease of the developing world, however several imported cases have been reported in different parts of the world and there are growing concerns of the potentials of Lassa fever Virus as a biological weapon. Yet no tangible solution to this problem has been developed nearly half a decade after its identification. Hence, the paper is aimed at appraising the problem...

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Pathogenesis of Lassa Fever

Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for hospitalized patients varying between 5-10%. Currently, there are no approved vaccines against Lassa fever for use in humans. Here, we review the publishe...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2012

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2012.05.170